For licensed healthcare professionals. The protocol figures below are drawn from published labeling and peer-reviewed literature for educational reference. They are not a prescription, not a recommendation, and not a substitute for the dispensing pharmacy's labeling or your own clinical judgment.

Sexual Health

PT-141

aka Bremelanotide, Vyleesi

Not WADA-listed

Melanocortin receptor agonist FDA-approved for hypoactive sexual desire disorder in premenopausal women. SC injection on-demand.

At a glance

Common vial size: 10 mg
Reference dose: 1.75 mg
Frequency: PRN — max 1 dose/24 h, 8 doses/month

Reference titration protocol

500 mcg × 8 wks → 1000 mcg × 4 wks → 1500 mcg × 4 wks, once daily.

Reference titration ladder for PT-141
Step	Dose	Duration	Administrations / week
1	500 mcg	4 weeks	7×
2	1 mg	4 weeks	7×
3	1.5 mg	4 weeks	7×

Reconstitution example

A 10 mg vial reconstituted with 3 mL of bacteriostatic water yields 3.333 mg/mL. Confirm the diluent and volume against the labeling that ships with the vial.

Open this configuration in the calculator

Clinical notes

Transient BP elevation — avoid in uncontrolled hypertension

Available formulations

Presentations carried across the VitaRelay pharmacy network, including 503A compounded, 503B outsourcing facility, and research & development sourcing. Pricing and state-level availability are shown to verified accounts only.

Injectable503A
Lyophilized PowderRUO
Nasal Spray503A
Pen503B

References

FDA label (Vyleesi)

Often used with

Compounds commonly discussed alongside PT-141 in published protocols and prescriber requests. Listed for reference only — not a clinical recommendation, and not a suggestion to co-administer.

Pricing and ordering are for verified accounts

VitaRelay serves licensed practices, prescribers, and pharmacies. Catalog pricing, availability by state, and ordering are available after your account is verified.

Also in Sexual Health

Oxytocin

Nonapeptide hormone with social-bonding and sexual-response effects. Compounded sublingual/nasal/troche forms used off-label.

Educational information for licensed healthcare professionals

The material on this page is general educational information intended for licensed healthcare professionals and their clinical staff. It is not medical advice, is not a substitute for professional judgment, and does not establish a provider-patient relationship. Nothing here should be read as a recommendation for, or endorsement of, any specific therapy, product, or course of treatment. Compounded preparations must be handled in accordance with applicable federal and state law, the dispensing pharmacy's labeling, and your own institutional policies. All clinical decisions — including product selection, preparation, dosing, and administration — remain the sole responsibility of the treating licensed practitioner.

VitaRelay is a technology and logistics network. We are not a pharmacy, prescriber, or distributor. See our Terms of Service and service availability for details.